Effect the Mechanism of Emodin Combined with Cp-1 on Proliferation and Apoptosis of Bladder Cancer Cell Line BIU-87

To investigate the effect of emodin combined with Cp-1 on proliferation and apoptosis bladder cancer cell line BIU-87. BIU-87 cells were randomly divided into control group, group. Flow cytometry was used to detect cells. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide assay Western blot reverse transcription–polymerase chain reaction recepteur d’origine nantais, Caspase-3 B-cell lymphoma 2 expressions. Compared survival rate group groupwas significantly decreased, especially in which lower than that (p<0.05), while increased, higher (p<0.05) expression nantais decreased (p<0.05). Inhibition suppressed increased Our results indicated could enhance inhibit The mechanism may be can down regulated 2, caspase-3 promoted